Importancia de las Aflatoxinas y Fumonisinas en Algunos Animales Domésticos
Palabras clave:
contaminante, carcinógeno, intoxicación, metabolito, toxicidadResumen
Las micotoxinas son compuestos químicos de bajo peso molecular, producidos por hongos, que tienen efectos patológicos, tanto en seres humanos como en animales. Aunque el número total de micotoxinas se desconoce y se estima que existen miles de metabolitos fúngicos, potencialmente tóxicos, entre las micotoxinas de mayor preocupación, se encuentran: Aflatoxinas, Tricotecenos (Vomitoxina, Nivalenol, Neosolaniol, Toxina T2, Diacetoxyscirpenol), Zearalenona, Fumonisinas, Ocratoxina A, Citrinina, Esterigmatocistina, Ácido Ciclopiazónico, Patulina, alcaloides del Ergot, y Moniliformina. Estas micotoxinas se encuentran en la mayor parte de los insumos de la industria pecuaria, entre los que se pueden mencionar el maíz, el sorgo, la soya, los ensilados, la pasta de algodón e incluso la leche.
Biografía del autor/a
Sandra Paola Rodríguez
Médico Veterinario Zootecnista. Especialista en Epidemiología.
Docente Facultad de Ciencias Agrarias.
Fundación Universitaria Juan de Castellanos.
Referencias bibliográficas
Angsubhakorn, S., Poomvises, P., Romruen, K.D. & Newberne, P.M. (1981). Aflatoxicosis in horses. American Veterinary Medical Association, 178, 274-278.
Arellano, J. (2003). Métodos de determinación, identificación y control de Micotoxinas en Ingredientes para la nutrición animal. Asociación Mexicana de Nutrición Animal. Recuperado de http://www.produccion-animal.com.ar.
Caloni, F., Spotti, M., Auerbach, H., Opden Camp, H., Fink Gremmels, J. & Pompa, G. (2000). In vitro metabolism of Fumonisin B1 by ruminal microflora. Veterinary Research Communications, 24 (6), 379-387.
Creppy, E., (2002). Update of survey, regulation and toxic effects of mycotoxins in Europe. Toxicology Letters, 127, 19-28.
Díaz, G.J. y Herman, B.J. (1994). Fumonisin toxicosis in domestic animals. Veterinary & Human Toxicology, 36 (6), 548-555.
D’Mello, J.P.F. & Macdonald, A.M.C. (1997). Mycotoxins. Animal Feed Science and Technology, 69, 155-166.
Engelhardt, J.A., Carlton, W.W. & Tuite, J.F. (1989). Toxicity of Fusarium moniliforme var. subglutinalis for chicks, ducklings and turkey poults. Avian Diseases, 33, 357-360.
Fink-Gremmels, J. (1999). Mycotoxins: their implications for human and animal health. The Veterinary Quarterly, 21,115-120.
Gavin L.M., (2002). Clinical Techniques in Equine Practice. 1(2), 89-93.
Haschek, W.M., Gumbrecht, L.A., Smith, G. & Tumbleson, P.D., (2001). Fumonisin toxicosis in swinean overview of porcine pulmonary edema and current perspective. Environmental Health Perspective, 109, (2), 251-257.
Hussein, S.H. & Basel, J.M. (2001).Toxicity, metabolism and impact of mycotoxins in humans and animals. Toxicology, 167 (2), 101-134.
Johnson, P.J., Casteel, S.W. & Messer, N.T. (1997). Effect of feeding deoxynivalenol (vomitoxin)-contaminated barley to horses. Journal of Veterinary Diagnostic Investigation, 9, 219-221.
Larsen, J.C., Hunt, J., Perrin, I. & Ruckenbauer, P. (2004). Workshop on trichothecenes with a focus on DON: summary report. Toxicology Letters, 153, 1-22.
Larsson, P.E., Tyden, E. & Tjalve, H. (2003). Cell-specific activation of aflatoxin B1 correlates with presence of some cytochrome P-450 enzymes in olfactory and respiratory tissues in horse. Research in
Veterinary Science, 74 (3), 227-233.
Marasas, W.F.O., Wehner, F.C., Van Rensburg, S.J. & Van Schalwik, D.J. (1981). Mycoflora of corn produced in human esophageal cancer areas of Transkei, Southern Africa. Phytopathology, 71, 792-796.
Mc Lean, M. & Dutton, M.F. (1995). Cellular interactions and metabolism of aflatoxin –an update. Pharmacology & therapeutics, 65, 163-192.
Meloche, J.L. & Smith, T.K. (1995). Altered tissue amino acid metabolism in acute T-2 toxicosis. Proceedings of the Society for Experimental Biology and Medicine, 210, 260-266.
Neal, G.E., Eaton, D.L., Judah, D.J. & Verma, A. (1998). Metabolism and toxicity of aflatoxins M1 and B1 in human-derived in vitro system. Toxicology and Applied Pharmacology, 151, 152-158.
Newman, K.E. (2005). Mycotoxins in equine diets: the difference between win, place and show?. En Lyons, T.P. & Jacques, K.A., (Eds). Nutritional Biotechnology in the feed and food industries (pp.
435-446). Nottingham: Nottingham University Press.
Osweiler, G.D., Ross, P.F., Witte, S., Carson, T.L., Rice, L.G. & Nelson, H.A. (1992). Characterization of an epizootic of pulmonary edema in swine associated with fumonisin in corn screenings. Journal of
Veterinary Diagnostic Investigation, 4, 53-59.
Otokawa, M. (1983). Immunological disorders. En Ueno (Ed.). Trichothecenes-Chemical, biological and toxicological aspects (pp. 163-170). New York: Elsevier.
Placinta, C.M., D’Mello, J.P.F. & Macdonald, A.M.C. (1999). A review of worldwide contamination of cereal grains and animal feed with Fusarium mycotoxins. Animal Feed Science and Technology, 78, 21-37.
Prelusky, D.B., Miller, J.D., Trenholm, H.L., Rotter, B.A., Savard, M.E., Yeung, J.M. & Scott, P.M. (1996). Biological fate of FB1 in foodproducing animals. Fumonisin in food. En Jakson (Ed.). Advances in Experimental Medicine and Biology. New York.
Trenholm, H.L., Foster, B.C., Charmely, L.L., Thompson, B.K., Hartin, K.E., Coppock, R.W. & Albassam, M.A. (1994). Effects of feeding diets containing Fusarium (naturally) contaminated wheat or pure deoxynivalenol (DON) in growing pigs. Canadian Journal of Animal Science, 74, 361-369.
World Health Organization (1993). International agency for research on cancer (IARC), Monographs on evaluation of carcinogenic risks to human.
Arellano, J. (2003). Métodos de determinación, identificación y control de Micotoxinas en Ingredientes para la nutrición animal. Asociación Mexicana de Nutrición Animal. Recuperado de http://www.produccion-animal.com.ar.
Caloni, F., Spotti, M., Auerbach, H., Opden Camp, H., Fink Gremmels, J. & Pompa, G. (2000). In vitro metabolism of Fumonisin B1 by ruminal microflora. Veterinary Research Communications, 24 (6), 379-387.
Creppy, E., (2002). Update of survey, regulation and toxic effects of mycotoxins in Europe. Toxicology Letters, 127, 19-28.
Díaz, G.J. y Herman, B.J. (1994). Fumonisin toxicosis in domestic animals. Veterinary & Human Toxicology, 36 (6), 548-555.
D’Mello, J.P.F. & Macdonald, A.M.C. (1997). Mycotoxins. Animal Feed Science and Technology, 69, 155-166.
Engelhardt, J.A., Carlton, W.W. & Tuite, J.F. (1989). Toxicity of Fusarium moniliforme var. subglutinalis for chicks, ducklings and turkey poults. Avian Diseases, 33, 357-360.
Fink-Gremmels, J. (1999). Mycotoxins: their implications for human and animal health. The Veterinary Quarterly, 21,115-120.
Gavin L.M., (2002). Clinical Techniques in Equine Practice. 1(2), 89-93.
Haschek, W.M., Gumbrecht, L.A., Smith, G. & Tumbleson, P.D., (2001). Fumonisin toxicosis in swinean overview of porcine pulmonary edema and current perspective. Environmental Health Perspective, 109, (2), 251-257.
Hussein, S.H. & Basel, J.M. (2001).Toxicity, metabolism and impact of mycotoxins in humans and animals. Toxicology, 167 (2), 101-134.
Johnson, P.J., Casteel, S.W. & Messer, N.T. (1997). Effect of feeding deoxynivalenol (vomitoxin)-contaminated barley to horses. Journal of Veterinary Diagnostic Investigation, 9, 219-221.
Larsen, J.C., Hunt, J., Perrin, I. & Ruckenbauer, P. (2004). Workshop on trichothecenes with a focus on DON: summary report. Toxicology Letters, 153, 1-22.
Larsson, P.E., Tyden, E. & Tjalve, H. (2003). Cell-specific activation of aflatoxin B1 correlates with presence of some cytochrome P-450 enzymes in olfactory and respiratory tissues in horse. Research in
Veterinary Science, 74 (3), 227-233.
Marasas, W.F.O., Wehner, F.C., Van Rensburg, S.J. & Van Schalwik, D.J. (1981). Mycoflora of corn produced in human esophageal cancer areas of Transkei, Southern Africa. Phytopathology, 71, 792-796.
Mc Lean, M. & Dutton, M.F. (1995). Cellular interactions and metabolism of aflatoxin –an update. Pharmacology & therapeutics, 65, 163-192.
Meloche, J.L. & Smith, T.K. (1995). Altered tissue amino acid metabolism in acute T-2 toxicosis. Proceedings of the Society for Experimental Biology and Medicine, 210, 260-266.
Neal, G.E., Eaton, D.L., Judah, D.J. & Verma, A. (1998). Metabolism and toxicity of aflatoxins M1 and B1 in human-derived in vitro system. Toxicology and Applied Pharmacology, 151, 152-158.
Newman, K.E. (2005). Mycotoxins in equine diets: the difference between win, place and show?. En Lyons, T.P. & Jacques, K.A., (Eds). Nutritional Biotechnology in the feed and food industries (pp.
435-446). Nottingham: Nottingham University Press.
Osweiler, G.D., Ross, P.F., Witte, S., Carson, T.L., Rice, L.G. & Nelson, H.A. (1992). Characterization of an epizootic of pulmonary edema in swine associated with fumonisin in corn screenings. Journal of
Veterinary Diagnostic Investigation, 4, 53-59.
Otokawa, M. (1983). Immunological disorders. En Ueno (Ed.). Trichothecenes-Chemical, biological and toxicological aspects (pp. 163-170). New York: Elsevier.
Placinta, C.M., D’Mello, J.P.F. & Macdonald, A.M.C. (1999). A review of worldwide contamination of cereal grains and animal feed with Fusarium mycotoxins. Animal Feed Science and Technology, 78, 21-37.
Prelusky, D.B., Miller, J.D., Trenholm, H.L., Rotter, B.A., Savard, M.E., Yeung, J.M. & Scott, P.M. (1996). Biological fate of FB1 in foodproducing animals. Fumonisin in food. En Jakson (Ed.). Advances in Experimental Medicine and Biology. New York.
Trenholm, H.L., Foster, B.C., Charmely, L.L., Thompson, B.K., Hartin, K.E., Coppock, R.W. & Albassam, M.A. (1994). Effects of feeding diets containing Fusarium (naturally) contaminated wheat or pure deoxynivalenol (DON) in growing pigs. Canadian Journal of Animal Science, 74, 361-369.
World Health Organization (1993). International agency for research on cancer (IARC), Monographs on evaluation of carcinogenic risks to human.
Cómo citar
Rodríguez, S. P. (2011). Importancia de las Aflatoxinas y Fumonisinas en Algunos Animales Domésticos. Conexión Agropecuaria JDC, 1(1), 37–44. Recuperado a partir de https://revista.jdc.edu.co/index.php/conexagro/article/view/346
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Publicado
2011-07-05
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Artículos de investigación Científica y tecnológica
